Pioglitazone: More than just an insulin sensitizer

Periostin: more than just an adhesion molecule.

The form and function of the heart is determined by the dynamic interaction of both intra and extracellular signals. During normal growth of the neonatal heart myocytes undergo hypertrophy in response to variety of signals including changes in blood pressure1–3. The number of fibroblasts also increase and the collagenous connective tissue is formed.4,7,8 The coordination of these postnatal sign...

Scabies: more than just an irritation.

Human scabies, caused by skin infestation with the arthropod mite, Sarcoptes scabiei, typically results in a papular, intensely pruritic eruption involving the interdigital spaces, and flexure creases. Recent research has led to a reassessment of the morbidity attributable to this parasite in endemic communities, particularly resulting from secondary skin sepsis and postinfective complications ...

Glycosylphosphatidylinositols: More than just an anchor?

There is increasing interest in the role of glycosylphosphatidylinositol (GPI) anchors that attach some proteins to cell membranes. Far from being biologically inert, GPIs influence the targeting, intracellular trafficking and function of the attached protein. Our recent paper demonstrated the role of sialic acid on the GPI of the cellular prion protein (PrP(C)). The "prion diseases" arise foll...

Much more than just an interview.

More than just vanilla.